Strohalm, Jirí: search on Z-Library

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1

Polyelectrolyte Vectors for Gene Delivery: Influence of Cationic Polymer on Biophysical Properties of Complexes Formed with DNA

Wolfert, Margreet A., Dash, Philip R., Nazarova, Ola, Oupicky, David, Seymour, Leonard W., Smart, Sarah, Strohalm, Jiri, Ulbrich, Karel

Journal:

Bioconjugate Chemistry

Year:

1999

Language:

english

File:

PDF, 268 KB

english, 1999

2

Analysis of tryptophan surface accessibility in proteins by MALDI-TOF mass spectrometry

Martin Strohalm, Jiří Šantrůček, Radovan Hynek, Milan Kodíček

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 320 KB

english, 2004

3

Novel IL-2-Poly(HPMA)Nanoconjugate Based Immunotherapy

Votavova, Petra, Tomala, Jakub, Subr, Vladimir, Strohalm, Jiri, Ulbrich, Karel, Rihova, Blanka, Kovar, Marek

Journal:

Journal of Biomedical Nanotechnology

Year:

2015

Language:

english

File:

PDF, 3.30 MB

english, 2015

4

The Same Drug but a Different Mechanism of Action: Comparison of Free Doxorubicin with Two Different N -(2-Hydroxypropyl)methacrylamide Copolymer-Bound Doxorubicin Conjugates in EL-4 Cancer Cell Line

Kovář, Lubomír, Strohalm, Jiří, Chytil, Petr, Mrkvan, Tomáš, Kovář, Marek, Hovorka, Ondřej, Ulbrich, Karel, Říhová, Blanka

Journal:

Bioconjugate Chemistry

Year:

2007

Language:

english

File:

PDF, 478 KB

english, 2007

5

Thermal diffusivity estimation of the olive oil during its high-pressure treatment

Miroslav Kubásek, Milan Houška, Aleš Landfeld, Jan Strohalm, Jiří Kamarád, Rudolf Žitný

Journal:

Journal of Food Engineering

Year:

2006

Language:

english

File:

PDF, 377 KB

english, 2006

6

Pinocytic capture and exocytosis of rat immunoglobulin IgG-N-(2-hydroxy-propyl)methacrylamide copolymer conjugates by rat visceral yolk sacs culturedin vitro

Ruth Duncan, Hazel C. Cable, Jiri Strohalm, Jindřich Kopeček

Journal:

Bioscience Reports

Year:

1986

Language:

english

File:

PDF, 467 KB

english, 1986

7

HPMA copolymer conjugates with reduced anti-CD20 antibody for cell-specific drug targeting. I. Synthesis and in vitro evaluation of binding efficacy and cytostatic activity

Tomáš Etrych, Jiří Strohalm, Lubomír Kovář, Martina Kabešová, Blanka Říhová, Karel Ulbrich

Journal:

Journal of Controlled Release

Year:

2009

Language:

english

File:

PDF, 598 KB

english, 2009

8

Activity of N-(2-hydroxypropyl)methacrylamide copolymers containing daunomycin against a rat tumour model

James Cassidy, Ruth Duncan, Gilmour J.Morrison, Jiri Strohalm, Dana Plocova, Jindrich Kopecek, Stanley B.Kaye

Journal:

Biochemical Pharmacology

Year:

1989

Language:

english

File:

PDF, 360 KB

english, 1989

9

Poly(ethylene glycol)s containing enzymatically degradable bonds

Karel Ulbrich, Jiří Strohalm, Jindřich Kopeček

Journal:

Macromolecular Chemistry and Physics

Year:

1986

Language:

english

File:

PDF, 613 KB

english, 1986

10

HPMA copolymer-doxorubicin conjugates: The effects of molecular weight and architecture on biodistribution and in vivo activity

Etrych, Tomáš, Šubr, Vladimír, Strohalm, Jiří, Šírová, Milada, Říhová, Blanka, Ulbrich, Karel

Journal:

Journal of Controlled Release

Year:

2012

Language:

english

File:

PDF, 793 KB

english, 2012

11

Poly[N-(2-Hydroypropyl)Methacrylamide] Conjugates of Bovine Seminal Ribonuclease. Synthesis, Physicochemical, and Preliminary Biological Evaluation

Ulbrich, Karel, Strohalm, Jirí, Plocová, Daniela, Oupický, David, Subr, Vladimir, Soucek, Josef, Poucková, Pavla, Matoušek, Josef

Journal:

Journal of Bioactive and Compatible Polymers

Year:

2000

File:

PDF, 1.73 MB

2000

12

Chemotherapy based on HPMA copolymer conjugates with pH-controlled release of doxorubicin triggers anti-tumor immunity

Tomas Mrkvan, Milada Sirova, Tomas Etrych, Petr Chytil, Jiri Strohalm, Dana Plocova, Karel Ulbrich, Blanka Rihova

Journal:

Journal of Controlled Release

Year:

2005

Language:

english

File:

PDF, 154 KB

english, 2005

13

Gamma Scintigraphy of the Biodistribution of 123 I-Labelled N-(2-Hydroxypropyl)methacrylamide Copolymer-Doxorubicin Conjugates in Mice with Transplanted Melanoma and Mammary Carcinoma

Pimm, Malcolm V., Perkins, Alan C., Strohalm, Jiri, Ulbrich, Karel, Duncan, Ruth

Journal:

Journal of Drug Targeting

Year:

1996

Language:

english

File:

PDF, 998 KB

english, 1996

14

Polymers containing enzymatically degradable bonds, 4. Preliminary experiments in vivo

Jindřich Kopeček, Irena Cífková, Pavla Rejmanová, Jiří Strohalm, Blahoslav Obereigner, Karel Ulbrich

Journal:

Macromolecular Chemistry and Physics

Year:

1981

Language:

english

File:

PDF, 396 KB

english, 1981

15

Heat transfer with heating and cooling granular materials in a scraped-surface homogeniser

Ales Landfeld, Karel Kyhos, Jan Strohalm, Jiri Sestak, Milan Houska

Journal:

Journal of Food Engineering

Year:

2006

Language:

english

File:

PDF, 186 KB

english, 2006

16

Biodegradable star HPMA polymer–drug conjugates: Biodegradability, distribution and anti-tumor efficacy

Tomáš Etrych, Lubomír Kovář, Jiří Strohalm, Petr Chytil, Blanka Říhová, Karel Ulbrich

Journal:

Journal of Controlled Release

Year:

2011

Language:

english

File:

PDF, 822 KB

english, 2011

17

Biodegradable drug carriers based on poly(ethylene glycol) block copolymers

Michal Pechar, Jiří Strohalm, Karel Ulbrich, Etienne Schacht

Journal:

Macromolecular Chemistry and Physics

Year:

1997

Language:

english

File:

PDF, 614 KB

english, 1997

18

Early Phase Tumor Accumulation of Macromolecules: A Great Difference in Clearance Rate between Tumor and Normal Tissues

Youichiro Noguchi, Jun Wu, Ruth Duncan, Jiří Strohalm, Karel Ulbrich, Takaaki Akaike, Hiroshi Maeda

Journal:

Year:

1998

Language:

english

File:

PDF, 116 KB

english, 1998

19

Biodegradable star HPMA polymer conjugates of doxorubicin for passive tumor targeting

Tomáš Etrych, Jiří Strohalm, Petr Chytil, Peter Černoch, Larisa Starovoytova, Michal Pechar, Karel Ulbrich

Journal:

European Journal of Pharmaceutical Sciences

Year:

2011

Language:

english

File:

PDF, 592 KB

english, 2011

20

Synthesis of Biodegradable Polymers for Controlled Drug Release

KAREL ULBRICH, MICHAL PECHAR, JIŘÍ STROHALM, VLADIMÍR ŠUBR, BLANKA ŘÍHOVÁ

Journal:

Annals of the New York Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 492 KB

english, 1997

21

Polymers containing enzymatically degradable bonds, 3. Poly[N-(2-hydroxypropyl)methacrylamide] chains connected by oligopeptide sequences cleavable by trypsin

Karel Ulbrich, Jiří Strohalm, Jindřich Kopeček

Journal:

Macromolecular Chemistry and Physics

Year:

1981

Language:

english

File:

PDF, 529 KB

english, 1981

22

Cytostatic and immunomobilizing activities of polymer-bound drugs: experimental and first clinical data

Blanka Řı́hová, Jiřı́ Strohalm, Jana Prausová, Katerina Kubáčková, Markéta Jelı́nková, Lad’ka Rozprimová, Milada Šı́rová, Dana Plocová, Tomáš Etrych, Vladimı́r Šubr, Tomáš Mrkvan, Marek Kovář, Karel U

Journal:

Journal of Controlled Release

Year:

2003

Language:

english

File:

PDF, 331 KB

english, 2003

23

Reactivity of histidine and lysine side-chains with diethylpyrocarbonate — A method to identify surface exposed residues in proteins

Aleš Hnízda, Jiří Šantrůček, Miloslav Šanda, Martin Strohalm, Milan Kodíček

Journal:

Journal of Biochemical and Biophysical Methods

Year:

2008

Language:

english

File:

PDF, 432 KB

english, 2008

24

Anti-Lymphoma Efficacy Comparison of Anti-Cd20 Monoclonal Antibody-Targeted and Non-Targeted Star-Shaped Polymer-Prodrug Conjugates

Lidický, Ondřej, Janoušková, Olga, Strohalm, Jiří, Alam, Mahmudul, Klener, Pavel, Etrych, Tomáš

Journal:

Year:

2015

Language:

english

File:

PDF, 1.76 MB

english, 2015

25

Doxorubicin attached to HPMA copolymer via amide bond modifies the glycosylation pattern of EL4 cells

Lubomir Kovar, Tomas Etrych, Martina Kabesova, Vladimir Subr, David Vetvicka, Ondrej Hovorka, Jiri Strohalm, Jan Sklenar, Petr Chytil, Karel Ulbrich, Blanka Rihova

Journal:

Year:

2010

Language:

english

File:

PDF, 430 KB

english, 2010

26

The pharmacokinetics of polymer-bound adriamycin

Len W. Seymour, Karel Ulbrich, Jiri Strohalm, Jindřich Kopeček, Ruth Duncan

Journal:

Biochemical Pharmacology

Year:

1990

Language:

english

File:

PDF, 781 KB

english, 1990

27

Intraperitoneal and subcutaneous retention of a soluble polymeric drug-carrier bearing galactose

Len W. Seymour, Ruth Duncan, Vladimir Chytrý, Jiri Strohalm, Karel Ulbrich, Jindrich Kopeček

Journal:

Journal of Controlled Release

Year:

1991

Language:

english

File:

PDF, 787 KB

english, 1991

28

HPMA based macromolecular therapeutics: Internalization, intracellular pathway and cell death depend on the character of covalent bond between the drug and the peptidic spacer and also on spacer composition

HOVORKA, ONDŘEJ, Etrych, TOMáš, Šubr, Vladimír, Strohalm, JIŘí, Ulbrich, Karel, Říhová, Blanka

Journal:

Journal of Drug Targeting

Year:

2006

Language:

english

File:

PDF, 1.61 MB

english, 2006

29

Overcoming multidrug resistance via simultaneous delivery of cytostatic drug and P-glycoprotein inhibitor to cancer cells by HPMA copolymer conjugate

Sivak, Ladislav, Subr, Vladimir, Tomala, Jakub, Rihova, Blanka, Strohalm, Jiri, Etrych, Tomas, Kovar, Marek

Journal:

Year:

2016

Language:

english

File:

PDF, 5.61 MB

english, 2016

30

High pressure and foods—fruit/vegetable juices

Milan Houška, Jan Strohalm, Kateřina Kocurová, Jiří Totušek, Danuše Lefnerová, Jan Tříska, Naděžda Vrchotová, Vlasta Fiedrleová, Maria Holasova, Dana Gabrovská, Ivana Paulíčková

Journal:

Journal of Food Engineering

Year:

2006

Language:

english

File:

PDF, 173 KB

english, 2006

31

Gamma Scintigraphy of a 123 I-Labelled N-(2-Hydroxypropyl)Methacrylamide Copolymer-Doxorubicin Conjugate Containing Galactosamine Following Intravenous Administration to Nude Mice Bearing Hepatic Human Colon Carcinoma

Pimm, Malcolm V., Perkins, Alan C., Strohalm, Jiri, Ulbrich, Karel, Duncan, Ruth

Journal:

Journal of Drug Targeting

Year:

1996

Language:

english

File:

PDF, 812 KB

english, 1996

32

Comparison of the binding kinetics of antibody-targeted N-(2-hydroxypropyl) methacrylamide (HPMA)-bound doxorubicin in vitro and in vivo

Marek Št'astný, Blanka Říhová, Jiří Strohalm, Karel Ulbrich

Journal:

Journal of Controlled Release

Year:

1996

Language:

english

File:

PDF, 583 KB

english, 1996

33

Spectral analysis of doxorubicin accumulation and the indirect quantification of its DNA intercalation

Ondřej Hovorka, Vladimír Šubr, David Větvička, Lubomír Kovář, Jiří Strohalm, Martin Strohalm, Aleš Benda, Martin Hof, Karel Ulbrich, Blanka Říhová

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2010

Language:

english

File:

PDF, 2.27 MB

english, 2010

34

Osmotic opening of the blood-brain barrier permeability to N-(2-hydroxypropyl)methacrylamide copolymers. Effect of polymer -Mw charge and hydrophobicity

Beth K. Armstrong, Quentin Smith, Stanley I. Rapoport, Jiří Strohalm, Jindřich Kopeček, Ruth Duncan

Journal:

Journal of Controlled Release

Year:

1989

Language:

english

File:

PDF, 852 KB

english, 1989

35

iBodies: Modular Synthetic Antibody Mimetics Based on Hydrophilic Polymers Decorated with Functional Moieties

Šácha, Pavel, Knedlík, Tomáš, Schimer, Jiří, Tykvart, Jan, Parolek, Jan, Navrátil, Václav, Dvořáková, Petra, Sedlák, František, Ulbrich, Karel, Strohalm, Jiří, Majer, Pavel, Šubr, Vladimír, Konvalinka

Journal:

Angewandte Chemie International Edition

Year:

2016

Language:

english

File:

PDF, 3.15 MB

english, 2016

36

The structure of polymer carriers controls the efficacy of the experimental combination treatment of tumors with HPMA copolymer conjugates carrying doxorubicin and docetaxel

Šírová, Milada, Strohalm, Jiří, Chytil, Petr, Lidický, Ondřej, Tomala, Jakub, Říhová, Blanka, Etrych, Tomáš

Journal:

Journal of Controlled Release

Year:

2017

Language:

english

File:

PDF, 1.16 MB

english, 2017

37

Treatment with HPMA copolymer-based doxorubicin conjugate containing human immunoglobulin induces long-lasting systemic anti-tumour immunity in mice

Milada Sirova, Jiri Strohalm, Vladimir Subr, Daniela Plocova, Pavel Rossmann, Tomas Mrkvan, Karel Ulbrich, Blanka Rihova

Journal:

Cancer Immunology, Immunotherapy

Year:

2007

Language:

english

File:

PDF, 666 KB

english, 2007

38

Star Structure of Antibody-Targeted HPMA Copolymer-Bound Doxorubicin: A Novel Type of Polymeric Conjugate for Targeted Drug Delivery with Potent Antitumor Effect

Kovář, Marek, Strohalm, Jiří, Etrych, Tomáš, Ulbrich, Karel, Říhová, Blanka

Journal:

Bioconjugate Chemistry

Year:

2002

Language:

english

File:

PDF, 167 KB

english, 2002

39

iBodies: Modular Synthetic Antibody Mimetics Based on Hydrophilic Polymers Decorated with Functional Moieties

Šácha, Pavel, Knedlík, Tomáš, Schimer, Jiří, Tykvart, Jan, Parolek, Jan, Navrátil, Václav, Dvořáková, Petra, Sedlák, František, Ulbrich, Karel, Strohalm, Jiří, Majer, Pavel, Šubr, Vladimír, Konvalinka

Journal:

Angewandte Chemie

Year:

2016

Language:

english

File:

PDF, 3.12 MB

english, 2016

40

Reduced cardiotoxicity of doxorubicin given in the form ofN-(2-hydroxypropyl) methacrylamide conjugates: an experimental study in the rat

Tai K. Yeung, John W. Hopewell, Rosemary H. Simmonds, Leonard W. Seymour, Ruth Duncan, Ornella Bellini, Maria Grandi, Federico Spreafico, Jiri Strohalm, Karel Ulbrich

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1991

Language:

english

File:

PDF, 805 KB

english, 1991

41

Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. 3. Evaluation of adriamycin conjugates against mouse leukaemia L1210 in vivo

Ruth Duncan, Isabella C. Hume, Pavla Kopečková, Karel Ulbrich, Jiří Strohalm, Jindřich Kopeček

Journal:

Journal of Controlled Release

Year:

1989

Language:

english

File:

PDF, 1.06 MB

english, 1989

42

Polymeric carriers of drugs for site-specific therapy

Ulbrich, Karel, Pechar, Michal, Strohalm, Jiři, Šubr, Vladimír, říhová, Blanka

Journal:

Macromolecular Symposia

Year:

1997

Language:

english

File:

PDF, 334 KB

english, 1997

43

Macromolecular prodrugs for use in targeted cancer chemotherapy: melphalan covalently coupled to N- (2-hydroxypropyl) methacrylamide copolymers

Ruth Duncan, Isabella C. Hume, Harold J. Yardley, Pauline A. Flanagan, Karel Ulbrich, Vladimir Subr, Jiri Strohalm

Journal:

Journal of Controlled Release

Year:

1991

Language:

english

File:

PDF, 1.43 MB

english, 1991

44

Polymers containing enzymatically degradable bonds. VI.Hydrophilic gels cleavable by chymotrypsin

Karel Ulbrich, Jiří Strohalm, Jindřich Kopeček

Journal:

Year:

1982

Language:

english

File:

PDF, 521 KB

english, 1982

45

Tyrosine residues modification studied by MALDI-TOF mass spectrometry

Jiří Šantrůček, Martin Strohalm, Vojtěch Kadlčík, Radovan Hynek, Milan Kodíček

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 274 KB

english, 2004

46

The structure-dependent toxicity, pharmacokinetics and anti-tumour activity of HPMA copolymer conjugates in the treatment of solid tumours and leukaemia

Tomalova, Barbora, Sirova, Milada, Rossmann, Pavel, Pola, Robert, Strohalm, Jiri, Chytil, Petr, Cerny, Viktor, Tomala, Jakub, Kabesova, Martina, Rihova, Blanka, Ulbrich, Karel, Etrych, Tomas, Kovar, M

Journal:

Journal of Controlled Release

Year:

2016

Language:

english

File:

PDF, 1.44 MB

english, 2016

47

Antitumor activity of IL-2/anti-IL-2 mAb immunocomplexes exerts synergism with that of N-(2-hydroxypropyl)methacrylamide copolymer-bound doxorubicin conjugate due to its low immunosuppressive activity

Jakub Tomala, Helena Chmelova, Jiri Strohalm, Karel Ulbrich, Milada Sirova, Blanka Rihova, Marek Kovar

Journal:

International Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 1.28 MB

english, 2011

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